This family consists of several caerin 1 proteins from Litoria species, Australian tree frogs. The caerin 1 peptides are among the most powerful of the broad-spectrum antibiotic amphibian peptides [PMID: 12717721]. These peptides are excreted from amphibian skin, and can interact with and disrupt bacterial membranes, leading to the permeabilisation of the cell membrane.

The below sequences were used to create Caerin sequence signatures:

The below sequences were retrieved using Caerin sequence signatures: