Halocidin

Halocidins are isolated from the haemocytes of the tunicate, Halocynthia aurantium (Sea peach). They are dimeric in structures, which are found via a disulphide linkage between cysteines of two different- sized monomers. Halocidins have been shown to have strong antimicrobial activities against a wide variety of pathogenic bacteria and could be ideal candidates as peptide antibiotics against multidrug-resistant bacteria [PMID: 12067731].

The below sequences were used to create Halocidin sequence signatures:

>CAMPSQ72
ALLHHGLNCAKGVLA
>CAMPSQ72
WLNALLHHGLNCAKGVLA

The below sequences were retrieved using Halocidin sequence signatures:

> CAMPHalP, CAMPHalH | CAMPSQ104 | P83706 | 41688534
ALLHHGLNCAKGVLA
> CAMPHalP, CAMPHalH | CAMPSQ105 | P83705 | 41688533
WLNALLHHGLNCAKGVLA
> CAMPHalP, CAMPHalH | CAMPSQ825 | P83716 | 635377411
DIDITGCSACKYAAG
2015, © Biomedical Informatics Centre, NIRRH, Mumbai