Thionins are small, basic plant proteins, 45 to 50 amino acids in length, which include three or four conserved disulphide linkages. The proteins are toxic to animal cells, presumably attacking the cell membrane and rendering it permeable: this results in the inhibition of sugar uptake and allows potassium and phosphate ions, proteins, and nucleotides to leak from cells [PMID: 3985614]. Thionins are mainly found in seeds where they may act as a defence against consumption by animals. A barley (Hordeum vulgare) leaf thionin that is highly toxic to plant pathogens and is involved in the mechanism of plant defence against microbial infections has also been identified [PMID: 1377959]. The hydrophobic protein crambin from the Abyssinian kale (Crambe abyssinica) is also a member of the thionin family [PMID: 3985614].
Sequences retrieved from pattern (1)
CAMPThiP K-S-C-C-x-[DNS]-T-x-[AG]-R-N-x-Y-N-x-C-R-x(2)-G-[AGT]  
  UniProt Name
  P07504 Thionin
  P09618 Leaf-specific thionin BTH6
  P01544 Alpha-purothionin, Purothionin AII
  P01543 Beta-purothionin
  A2YDH5 Thionin
Sequences retrieved from HMM ( 1 )
  GI UniProt Name
  135798 P07504 Thionin
  2507457 P09618 Leaf-specific thionin BTH6
  P01539 Phoratoxin
  350008 P01544 Alpha-purothionin, Purothionin AII
  229588 P01543 Beta-purothionin

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