CAMPSQ1162
Title : KR-12
GenInfo Identifier : 1706745
Source : Synthetic construct
NCBI Taxonomy : 9606
UniProt: P49913
PDB: 2FBS, 2FBU, 2FCG, 2K6O, 2LMF
Structure Database : CAMPST122, CAMPST560, CAMPST123, CAMPST167, CAMPST213
PubMed : 18818205
Length : 12
Activity : Antibacterial
Gram Nature : Gram-ve
Target : E.coli ML-35p, Pseudomonas aeruginosa, Listeria monocytogenes , S. aureus 930918-3 , S. aureus 710A , MRSA ATCC 33591 , S. epidermidis ATCC 49741
Hemolytic Activity : No cytotoxic effects on human cells till 63 mM
Validated : Experimentally Validated
Pfam : PF12153 : ( LPS binding domain of CAP18 (C terminal) )
PF00666 : ( Cathelicidin )
InterPro : IPR001894 : Cathelicidin.
IPR018216 : Cathelicidin_CS.
IPR022746 : Cathlecidin_C.
AMP Family : Cathelicidin
Signature :
ID Type Pattern / HMM T. Length
CAMPCatH HMM Variable
CAMPCatH37 HMM 37
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005618 Cellular Component Cell wall TAS
GO:0005829 Cellular Component Cytosol TAS
GO:0005576 Cellular Component Extracellular region IEA
GO:0042742 Biological Process Defense response to bacterium TAS
GO:0051701 Biological Process Interaction with host TAS
GO:0051873 Biological Process Killing by host of symbiont cells IDA
GO:0044140 Biological Process Negative regulation of growth of symbiont on or near host surface IDA
GO:0090382 Biological Process Phagosome maturation TAS
Sequence:
KRIVQRIKDFLR