Prepromelittin-related peptide

CAMPSQ156

Title :

GenInfo Identifier :

154347368

Source :

Rana tagoi [Tago frog]

Taxonomy :

Animalia, Amphibians

NCBI Taxonomy :

113384

UniProt:

A7BJK6

PubMed :

12804591

Length :

Activity :

Antibacterial, Antifungal, Anticancer

Gram Nature :

Gram+ve, Gram-ve

Target :

S. aureus ( MIC = 3. 5 microM ), E. coli ( MIC = 20 microM ), C. albicans ( MIC = 19 microM ), EL4 T-lymphoma cells ( MIC = 14 microM )

Hemolytic Activity :

Human erythrocytes (8 microM), L929 fibroblasts (20 microM)

Validated :

Experimentally Validated

Pfam :

PF03032 : ( Brevenin/esculentin/gaegurin/rugosin family )
PF01372 : ( Melittin )

InterPro :

IPR004275 : Brevinin.
IPR002116 : Melittin/Api_allergen.

AMP Family :

Melittin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPMelH	HMM		Variable

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0004860	Molecular Function	Protein kinase inhibitor activity	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA
GO:0006469	Biological Process	Negative regulation of protein kinase activity	IEA

Sequence:

AIGSILGALAKGLPTLISWIKNR