Antibacterial peptide PMAP-37

CAMPSQ199

Title :

GenInfo Identifier :

1709082

Source :

Sus scrofa [Pig]

Taxonomy :

Animalia, Mammals

NCBI Taxonomy :

9823

UniProt:

P49932

PubMed :

7737198

Length :

Activity :

Antibacterial

Gram Nature :

Gram+ve, Gram-ve

Target :

E.coli ML35 ( MIC = 2 microM), E.coli ATCC 25922 ( MIC = 1 microM), E.coli D21 ( MIC = 2 microM), S.typhimurium ATCC 14028 ( MIC = 4 microM), P.aeruginosa ATCC 27853 ( MIC = 2 microM), B.megaterium Bm11 ( MIC = 4 microM), B.megaterium local isolate ( MIC = 4 microM), S.aureus ATCC 25923 ( MIC = 32 microM), S.aureus Cowan 1 ( MIC = 64 microM)

Validated :

Experimentally Validated

Pfam :

PF12153 : ( LPS binding domain of CAP18 (C terminal) )
PF00666 : ( Cathelicidin )

InterPro :

IPR001894 : Cathelicidin.
IPR018216 : Cathelicidin_CS.
IPR022746 : Cathlecidin_C.

AMP Family :

Cathelicidin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPCatH	HMM		Variable
CAMPCatH37	HMM		37

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA

Sequence:

GLLSRLRDFLSDRGRRLGEKIERIGQKIKDLSEFFQS