CAMPSQ207
Title : Moronecidin
GenInfo Identifier : 17940118
Source : Morone saxatilis [Striped bass]
Taxonomy : Animalia, Pisces
NCBI Taxonomy : 34816
UniProt: Q8UUG0
PDB: 2JOS, 2OJM
Structure Database : CAMPST146, CAMPST650
PubMed : 11739390
Length : 23
Activity : Antibacterial
Gram Nature : Gram+ve, Gram-ve
Target : E.faecalis VRE ( MIC = 5-10 microM), E.faecalis ( MIC = 2.5-5 microM), Listeria monocytogenes ( MIC = 2.5-5 microM), M.luteus ( MIC = 10-20 microM), S.aureus MRSA ( MIC = 1.25-2.5 microM), Staphylococcus epidermitis ( MIC = 5-10 microM), Staphylococcus saprophiticus ( MIC = 5-10 microM), Staphylococcus xylosus ( MIC = >20 microM), Streptococcus agalactiae ( MIC = 1.25-2.5 microM), Streptococcus bovis ( MIC = 1.25-2.5 microM), Streptococcus equisimilis ( MIC = 2.5-5 microM), Streptococcus mitis ( MIC = 1.25-2.5 microM), Streptococcus Pneumonae ( MIC = 1.25-2.5 microM), Streptococcous pyrogenes ( MIC = 1.25-2.5 microM), S. iniae KST740 ak ( MIC = 1.25-2.5 microM), S.iniae KSTSi 6P ( MIC = 1.25-2.5 microM), A. Hydrophila ( MIC = >20 microM), Burkholderia cepacia ( MIC = >20 microM), Vibrio Cholera ( MIC = 2.5-5 microM), E.coli ( MIC = 5-10 microM), Enterobacter cloacae ( MIC = 10-20 microM), Enterobacter Aerogenes ( MIC = 10-20 microM), Klebsiella Pneumonae ( MIC = 2.5-5 microM), Klebsiella oxytoca ( MIC = 5-10 microM), Salmonella cholerasuis ( MIC = 10-20 microM), Salmonella typhimurium ( MIC = 10-20 microM), Salmonella arizonae ( MIC = 10-20 microM), S. marcescens ( MIC = >20 microM), S.flexneri ( MIC = 2.5-5 microM), Shigella sonnei ( MIC = 5-10 microM), Yersinia enterocolitica ( MIC = 2.5-5 microM), N.crassa ( MIC = 1.56-3.12 microM), A.fumigatus ( MIC = 50-100 microM), F.axysporum ( MIC = 0.78-1.56 microM), F.culmorum ( MIC = 0.39-0.78 microM), Candida ablicans ( MIC = 10-20 microM), Candida glabrata ( MIC = 10-20 microM), Candida lusitania ( MIC = 10-20 microM), Candida tropacalis ( MIC = 10-20 microM)
Hemolytic Activity : Hemolytic activity (10 microM -55HumanRBC, 11 SheepRBC), (20 microM -100HumanRBC, 51Sheep RBC), (40 microM -100HumanRBC, 80Sheep RBC), (80 microM -100HumanRBC, 100SheepRBC)
Validated : Experimentally Validated
Pfam : PF08107 : ( Pleurocidin family )
InterPro : IPR012515 : Antimicrobial12.
AMP Family : Pleurocidin
Signature :
ID Type Pattern / HMM T. Length
CAMPPleH23 HMM 23
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular Component Extracellular region IEA
GO:0019835 Biological Process Cytolysis IEA
GO:0042742 Biological Process Defense response to bacterium IEA
GO:0050832 Biological Process Defense response to fungus IEA
GO:0044179 Biological Process Hemolysis in other organism IEA
Sequence:
FFHHIFRGIVHVGKTIHRLVTGG