CAMPSQ282
Title : Gaegurin-4
GenInfo Identifier : 2506236
Source : Rana rugosa [Japanese wrinkled frog]
Taxonomy : Animalia, Amphibians
UniProt: P80398
PDB: 2G9L
Structure Database : CAMPST124
PubMed : 7999137
Length : 37
Activity : Antibacterial, Antifungal, Antiparasitic
Gram Nature : Gram+ve, Gram-ve
Target : Micrococcus luteus ( MIC = 2.5 microg/ml), Staphylococcus epidermidis ( MIC = 10 microg/ml), Bacillus subtilis ( MIC = 10 microg/ml), Klebsiella pneumoniae ( MIC = 25 microg/ml), Shigella dysentariae ( MIC = 25 microg/ml), Pseudomonas putida ( MIC = 100 microg/ml), Pseudomonas aeruginosa ( MIC = 100 microg/ml), Eshchericia coli ( MIC = 75 microg/ml), Saccharomyces cerevisiae ( MIC = 200 microg/ml), Candida albicans ( MIC = 200 microg/ml), Salmonella typhimurium ( MIC = 200 microg/ml), Proteus mirabilis ( MIC = >200 microg/ml), Serratia marcescens ( MIC = >200 microg/ml)
Validated : Experimentally Validated
Pfam : PF08023 : ( Frog antimicrobial peptide )
PF03032 : ( Brevenin/esculentin/gaegurin/rugosin family )
InterPro : IPR012521 : Antimicrobial_frog_2.
IPR004275 : Brevinin.
IPR018247 : EF_Hand_1_Ca_BS.
AMP Family : Gaegurin
Signature :
ID Type Pattern / HMM T. Length
CAMPRugP Pattern K-[ADQT]-x-A-x(2)-[ILV]-[AG]-K-x(4,5)-G-[AIV]-x(2)-[AGT]-[ALV] Variable
CAMPGaeH HMM Variable
CAMPRanH28 HMM 28
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular Component Extracellular region IEA
GO:0042742 Biological Process Defense response to bacterium IEA
Sequence:
GILDTLKQFAKGVGKDLVKGAAQGVLSTVSCKLAKTC