CAMPSQ3118
Title : Ascaphin-8
Source : Ascaphus truei [Coastal tailed frog]
Taxonomy : Animalia, Amphibians
UniProt: P0CJ32
PubMed : 15207717
Length : 19
Activity : Antibacterial, Antifungal
Gram Nature : Gram+ve, Gram-ve
Target : Escherichia coli ( MIC = 6 microM ), Staphylococcus aureus ( MIC = 6 microM ), Pseudomonas aeruginosa ( MIC = 50 microM ), Enterobacter cloacae ( MIC = 13 microM ), Klebsiella pneumoniae ( MIC = 25 microM ), Proteus mirabilis ( MIC > 100 microM ), S. epidermidis ( MIC =25 microM ), E. faecalis ( MIC > 100 microM ), Streptococcus Group B ( MIC = 13 microM ), C. albicans ( MIC = 100 microM )
Hemolytic Activity : Human erythrocytes ( HC50 = 50 microM )
Validated : Experimentally Validated
Signature :
ID Type Pattern / HMM T. Length
CAMPAscP Pattern G-F-[KR]-D-x-[IL]-K-G-A-A-K-x-[FL]-[IV]-K-T-V-[AL] Variable
CAMPAscH HMM Variable
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular Component Extracellular region IDA
GO:0019835 Biological Process Cytolysis IEA
GO:0050829 Biological Process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological Process Defense response to Gram-positive bacterium IDA
GO:0044179 Biological Process Hemolysis in other organism IDA
Sequence:
GFKDLLKGAAKALVKTVLF