Moronecidin

CAMPSQ373

Title :

Moronecidin

GenInfo Identifier :

37999868

Source :

Morone chrysops x Morone saxatilis [White bass x Striped bass]

Taxonomy :

Animalia, Pisces

UniProt:

Q8UUG2

PubMed :

11739390

Length :

Activity :

Antibacterial, Antifungal

Gram Nature :

Gram+ve, Gram-ve

Target :

E. faecalis ( MIC = 5?10 microM), E. faecalis ( MIC = 2.5?5 microM), Listeria monocytogenes ( MIC = 2.5?5 microM), M. luteus ( MIC = 10?20 microM), S. aureus ( MIC = 1.25?2.5 microM), Staphylococcus epidermidis ( MIC = 5?10 microM), Staphylococcus saprophiticus ( MIC = 5?10 microM), Staphylococcus xylosus ( MIC = >20 microM), Streptococcus agalactiae ( MIC = 1.25?2.5 microM), Streptococcus bovis ( MIC = 1.25?2.5 microM), Streptococcus equisimilis ( MIC = 2.5?5 microM), Streptococcus mitis ( MIC = 1.25?2.5 microM), Streptococcus pneumoniae ( MIC = 1.25?2.5 microM), Streptococcus pyogenes ( MIC = 1.25?2.5 microM), S. iniae, KST740ak ( MIC = 1.25?2.5 microM), S. iniae, KSTSi 6P ( MIC = 1.25?2.5 microM), A. hydrophila ( MIC = >20 microM), Burkholderia cepacia ( MIC = >20 microM), Vibrio cholera ( MIC = 2.5?5 microM), E. coli ( MIC = 5?10 microM), Enterobacter cloacae ( MIC = 10?20 microM), Enterobacter aerogenes ( MIC = 10?20 microM), Klebsiella pneumoniae ( MIC = 2.5?5 microM), Klebsiella oxytoca ( MIC = 5?10 microM), Moraxella catarrhalis ( MIC = 2.5?5 microM), N. gonorrhea ( MIC = >20 microM), P. aeruginosa ( MIC = 5?10 microM), Salmonella choleraesuis ( MIC = 10?20 microM), Salmonella typhimurium ( MIC = 10?20 microM), Salmonella arizonae ( MIC = 10?20 microM), S. marcescens ( MIC = >20 microM), S. flexneri ( MIC = 2.5?5 microM), Shigella sonnei ( MIC = 5?10 microM), Yersinia enterocolitica ( MIC = 2.5?5 microM), N. crassa ( MIC = 1.56?3.12 microM), A. fumigatus ( MIC = 50?100 microM), F. oxysporum ( MIC = 0.78?1.56 microM), F. culmorum ( MIC = 0.39?0.78 microM), Candida albicans ( MIC = 10-20 microM), Candida glabrata ( MIC = 10-20 microM), Candida lusitania ( MIC = 10-20 microM), Candida tropicalis ( MIC = 10-20 microM).

Validated :

Experimentally Validated

Pfam :

PF08107 : ( Pleurocidin family )

InterPro :

IPR012515 : Antimicrobial12.

AMP Family :

Pleurocidin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPPleH23	HMM		23

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA
GO:0050832	Biological Process	Defense response to fungus	IEA
GO:0031640	Biological Process	Killing of cells of other organism	IEA

Sequence:

FFHHIFRGIVHVGKTIHKLVTG