Jingdongin-1 antimicrobial peptide precursor

CAMPSQ4067

Title :

GenInfo Identifier :

425872851

Source :

Amolops jingdongensis [Chinese torrent frog]

Taxonomy :

Animalia, Amphibians

NCBI Taxonomy :

1077530

UniProt:

K7ZGS2

PubMed :

22828809

Length :

Activity :

Antibacterial, Antifungal

Gram Nature :

Gram+ve, Gram-ve

Target :

B. dysenteriae ( MIC=35 microg/ml ), S. aureus ATCC 2592 ( MIC=4.7 microg/ml ), B. subtilis ATCC 6633 ( MIC=9.38 microg/ml ), C. albicans ATCC 2002 ( MIC=18.75 microg/ml )

Hemolytic Activity :

Rabbit erythrocytes 1.32% lysis (25 microg/ml)

Validated :

Experimentally Validated

Comment :

Inactive against E. coli ATCC 25922 at a concentration of 200 microg/ml

Pfam :

PF03032 : ( Brevenin/esculentin/gaegurin/rugosin family )

InterPro :

IPR004275 : Brevinin.

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPBreH17	HMM		17

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA

Sequence:

FLPLFLPKIICVITKKC