Brevinin-1JDa

CAMPSQ4143

Title :

Brevinin-1JDa

GenInfo Identifier :

410591617

Source :

Odorrana jingdongensis [Jingdong frog]

Taxonomy :

Animalia, Amphibians

NCBI Taxonomy :

431936

UniProt:

B3A0M4

PubMed :

22917879

Length :

Activity :

Antibacterial

Gram Nature :

Gram+ve, Gram-ve

Target :

Staphylococcus aureus (ATCC 25923) ( MIC= 16 microg/ml ), Methicillin-resistant S. aureus (MRSA, CIB 85462) ( MIC= 32 microg/ml ), Escherichia coli (ATCC 25922) ( MIC= 128 microg/ml ), Extended-spectrum-lactamases E. coli (ESBL, CIB 84492) ( MIC= 64 microg/ml), Candida albicans ( MIC = 128microg/ml)

Hemolytic Activity :

Rabbit erythrocytes 79.2±6.8% lysis (128 microg/ml)

Validated :

Experimentally Validated

Pfam :

PF08018 : ( Frog antimicrobial peptide )

InterPro :

IPR012520 : Antimicrobial_frog_1.

AMP Family :

Brevinin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPBreH	HMM		Variable
CAMPBreH20	HMM		20

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0019835	Biological Process	Cytolysis	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA
GO:0050832	Biological Process	Defense response to fungus	IEA
GO:0044179	Biological Process	Hemolysis in other organism	IEA

Sequence:

FLPAVIRVAANVLPTVFCAISKKC