| CAMPSQ4151 |
| Title : |
Esculentin-2JDa |
| GenInfo Identifier : |
410591613 |
| Source : |
Odorrana jingdongensis [Jingdong frog] |
| Taxonomy : |
Animalia, Amphibians |
| NCBI Taxonomy : |
431936 |
| UniProt: |
B3A0M8 |
| PubMed : |
22917879 |
| Length : |
37 |
| Activity : |
Antibacterial |
| Gram Nature : |
Gram+ve, Gram-ve |
| Target : |
Staphylococcus aureus (ATCC 25923) ( MIC=32microg/ml ), Methicillin-resistant S. aureus (MRSA, CIB 85462) ( MIC=32microg/ml ), Escherichia coli (ATCC 25922) ( MIC=128microg/ml ), Extended-spectrum-lactamases E. coli (ESBL, CIB 84492) ( MIC=128microg/ml) |
| Hemolytic Activity : |
No detectable hemolysis at 128 microg/ml |
| Validated : |
Experimentally Validated |
| Comment : |
Inactive against Candida albicans |
| Pfam : |
PF08023 : ( Frog antimicrobial peptide )
|
| InterPro : |
IPR012521 : Antimicrobial_frog_2.
|
| AMP Family : |
Esculentin |
| Signature : |
| ID |
Type |
Pattern / HMM |
T. Length |
|
CAMPEscP37 |
Pattern |
K-x(2)-[AGT]-[KR]-x-G-x(3)-[ILMV]-[AGS]-C-K-[AIV]-x(2)-[EQ]-C |
37 |
|
CAMPEscH |
HMM |
 |
Variable |
|
CAMPEscH37 |
HMM |
|
37 |
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005576 |
Cellular Component |
Extracellular region |
IEA |
| GO:0042742 |
Biological Process |
Defense response to bacterium |
IEA |
|
Sequence: |
GLFTLIKGAAKLIGKTVAKEAGKTGLELMACKITNQC |
