Brevinin-2E

CAMPSQ455

Title :

Brevinin-2E

GenInfo Identifier :

416725

Source :

Rana esculenta (edible frog ) [Edible frog]

Taxonomy :

Animalia, Amphibians

UniProt:

P32413

PubMed :

8508915

Length :

Activity :

Antibacterial

Gram Nature :

Gram+ve, Gram-ve

Target :

E. coli D21 ( MIC = 0.5 microM), B. megaterium BmII ( MIC = 0.2 microM), S. aureus Cowan 1 ( MIC = 2.0microM), P.aeruginosa ATCC15692 ( MIC = >30microM)

Validated :

Experimentally Validated

Comment :

Inactive against C.albicans, Saccharomyces cerevisiae

Pfam :

PF08023 : ( Frog antimicrobial peptide )

InterPro :

IPR012521 : Antimicrobial_frog_2.

AMP Family :

Brevinin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPBreH	HMM		Variable
CAMPRanH28	HMM		28

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0019835	Biological Process	Cytolysis	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA
GO:0044179	Biological Process	Hemolysis in other organism	IEA

Sequence:

GIMDTLKNLAKTAGKGALQSLLNKASCKLSGQC