| CAMPSQ5779 |
| Title : |
Brevinin-2HS2A, Brevinin-2HS2B |
| GenInfo Identifier : |
544602101 |
| Source : |
Odorrana hainanensis [Odor frog] |
| Taxonomy : |
Animalia, Amphibians |
| UniProt: |
E7EKE0, E7EKE1 |
| PubMed : |
22450466 |
| Length : |
33 |
| Activity : |
Antibacterial, Antifungal |
| Gram Nature : |
Gram +ve, Gram -ve |
| Target : |
S.aureus ATCC 25923 ( MIC = 19 microM ), B.licheniformis X39 ( MIC = 37.5 microM ), R.rhodochrous X15 ( MIC = 9.5 microM ), P.faecalis X29 ( MIC = 9.5 microM ), C.albicans ATCC 2002 ( MIC = 19 microM ), slime mold 090223 ( MIC = 37.5 microM ) |
| Hemolytic Activity : |
Low hemolytic activity against human erythrocytes (LC (50)=300 uM). |
| Validated : |
Experimentally Validated |
| Comment : |
Virtually inactive against E.faecium 091299 (MIC=150 uM), S.carnosus KHS (MIC=150 uM) and inactive against E.faecalis 981, E.coli, P.aeruginosa ,S.typhi |
| Pfam : |
PF08023 : ( Frog antimicrobial peptide )
PF03032 : ( Brevenin/esculentin/gaegurin/rugosin family )
|
| AMP Family : |
Brevinin |
| Signature : |
| ID |
Type |
Pattern / HMM |
T. Length |
|
CAMPBreH |
HMM |
 |
Variable |
|
CAMPBreH29 |
HMM |
|
29 |
|
Sequence: |
SLLGTVKDLLIGAGKSAAQSVLKGLSCKLSKDC |
