CAMPSQ5779
Title : Brevinin-2HS2A, Brevinin-2HS2B
GenInfo Identifier : 544602101
Source : Odorrana hainanensis [Odor frog]
Taxonomy : Animalia, Amphibians
UniProt: E7EKE0, E7EKE1
PubMed : 22450466
Length : 33
Activity : Antibacterial, Antifungal
Gram Nature : Gram +ve, Gram -ve
Target : S.aureus ATCC 25923 ( MIC = 19 microM ), B.licheniformis X39 ( MIC = 37.5 microM ), R.rhodochrous X15 ( MIC = 9.5 microM ), P.faecalis X29 ( MIC = 9.5 microM ), C.albicans ATCC 2002 ( MIC = 19 microM ), slime mold 090223 ( MIC = 37.5 microM )
Hemolytic Activity : Low hemolytic activity against human erythrocytes (LC (50)=300 uM).
Validated : Experimentally Validated
Comment : Virtually inactive against E.faecium 091299 (MIC=150 uM), S.carnosus KHS (MIC=150 uM) and inactive against E.faecalis 981, E.coli, P.aeruginosa ,S.typhi
Pfam : PF08023 : ( Frog antimicrobial peptide )
PF03032 : ( Brevenin/esculentin/gaegurin/rugosin family )
AMP Family : Brevinin
Signature :
ID Type Pattern / HMM T. Length
CAMPBreH HMM Variable
CAMPBreH29 HMM 29
Sequence:
SLLGTVKDLLIGAGKSAAQSVLKGLSCKLSKDC