CAMPSQ598 |
Title : |
Brevinin-1E |
GenInfo Identifier : |
728978 |
Source : |
Rana esculenta (edible frog ) [Edible frog] |
Taxonomy : |
Animalia, Amphibians |
UniProt: |
P32412 , P84839 |
PubMed : |
8508915 |
Length : |
24 |
Activity : |
Antibacterial |
Gram Nature : |
Gram+ve, Gram-ve |
Target : |
E.coliD21 ( MIC = 1.8 microM), B.megaterium Bm11 ( MIC = 0.4 microM), S.aureus Cowan1 ( MIC = 0.6 microM), P.aeruginosa ATCC15692 ( MIC = 30.6 microM), C. albicans ( MIC = 4.7 microM), S. cerevisiae ( MIC = 3.8 microM) |
Hemolytic Activity : |
Red blood cells (0.5 microM) |
Validated : |
Experimentally Validated |
Pfam : |
PF08018 : ( Frog antimicrobial peptide )
PF03032 : ( Brevenin/esculentin/gaegurin/rugosin family )
|
InterPro : |
IPR012520 : Antimicrobial_frog_1.
IPR004275 : Brevinin.
|
AMP Family : |
Brevinin |
Signature : |
ID |
Type |
Pattern / HMM |
T. Length |
CAMPBreH |
HMM |
|
Variable |
CAMPBreH20 |
HMM |
|
20 |
|
Gene Ontology : |
GO ID |
Ontology |
Definition |
Evidence |
GO:0005576 |
Cellular Component |
Extracellular region |
IDA |
GO:0019835 |
Biological Process |
Cytolysis |
IEA |
GO:0050829 |
Biological Process |
Defense response to Gram-negative bacterium |
IDA |
GO:0050830 |
Biological Process |
Defense response to Gram-positive bacterium |
IDA |
GO:0044179 |
Biological Process |
Hemolysis in other organism |
IDA |
GO:0005576 |
Cellular Component |
Extracellular region |
IDA |
GO:0042742 |
Biological Process |
Defense response to bacterium |
IEA |
|
Sequence: |
FLPLLAGLAANFLPKIFCKITRKC |