CAMPSQ598
Title : Brevinin-1E
GenInfo Identifier : 728978
Source : Rana esculenta (edible frog ) [Edible frog]
Taxonomy : Animalia, Amphibians
NCBI Taxonomy : 8401, 70019
UniProt: P32412 , P84839
PubMed : 8508915
Length : 24
Activity : Antibacterial
Gram Nature : Gram+ve, Gram-ve
Target : E.coliD21 ( MIC = 1.8 microM), B.megaterium Bm11 ( MIC = 0.4 microM), S.aureus Cowan1 ( MIC = 0.6 microM), P.aeruginosa ATCC15692 ( MIC = 30.6 microM), C. albicans ( MIC = 4.7 microM), S. cerevisiae ( MIC = 3.8 microM)
Hemolytic Activity : Red blood cells (0.5 microM)
Validated : Experimentally Validated
Pfam : PF08018 : ( Frog antimicrobial peptide )
PF03032 : ( Brevenin/esculentin/gaegurin/rugosin family )
InterPro : IPR012520 : Antimicrobial_frog_1.
IPR004275 : Brevinin.
AMP Family : Brevinin
Signature :
ID Type Pattern / HMM T. Length
CAMPBreH HMM Variable
CAMPBreH20 HMM 20
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular Component Extracellular region IDA
GO:0019835 Biological Process Cytolysis IEA
GO:0050829 Biological Process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological Process Defense response to Gram-positive bacterium IDA
GO:0044179 Biological Process Hemolysis in other organism IDA
GO:0005576 Cellular Component Extracellular region IDA
GO:0042742 Biological Process Defense response to bacterium IEA
Sequence:
FLPLLAGLAANFLPKIFCKITRKC