| CAMPSQ734 |
| Title : |
Cathelicidin |
| GenInfo Identifier : |
38641346 |
| Source : |
Canis lupus familiaris [Dog] |
| Taxonomy : |
Animalia, Mammals |
| NCBI Taxonomy : |
9615 |
| UniProt: |
Q6TN20 |
| PubMed : |
17462733 |
| Length : |
38 |
| Activity : |
Antibacterial, Antifungal |
| Gram Nature : |
Gram+ve, Gram-ve |
| Target : |
Candida albicans ATCC 11006 (MIC = 44.33 microM), Candida albicans (hematogenous) ATCC 14053 (MIC = 11.08 microM), Escherichia coli ATCC 25922 (MIC = 1.11 microM), Escherichia coli ATCC 700336 (MIC = 1.11 microM), Escherichia coli ATCC 700378 (MIC = 1.11 microM), Escherichia coli ATCC BAA-457 (MIC = 1.11 microM), Klebsiella pneumoniae ATCC 10031 (MIC = 1.11 microM), Proteus mirabilis ATCC 12453 (MIC = 1.11 microM), Pseudomonas aeruginosa ATCC 10145 (MIC = 1.11 microM), Salmonella Enteritidis ATCC 13076 (MIC = 0.44 microM), Salmonella Typhimurium ATCC 13311 (MIC = 1.11 microM), Neisseria gonorrhoeae ATCC 10150 (MIC = 0.06 microM), Staphylococcus aureus ATCC 10832 (MIC = 44.33 microM), Listeria monocytogenes ATCC 19115 (MIC = 0.44 microM), Ureaplasma canigenitalium ATCC 51252 (MIC = 0.06 microM), Ureaplasma urealyticum ATCC 27619 (MIC = 44.33 microM) |
| Validated : |
Experimentally Validated |
| Pfam : |
PF12153 : ( LPS binding domain of CAP18 (C terminal) )
PF00666 : ( Cathelicidin )
|
| InterPro : |
IPR001894 : Cathelicidin.
IPR022746 : Cathlecidin_C.
|
| AMP Family : |
Cathelicidin |
| Signature : |
| ID |
Type |
Pattern / HMM |
T. Length |
|
CAMPCatH |
HMM |
 |
Variable |
|
CAMPCatH37 |
HMM |
|
37 |
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005576 |
Cellular Component |
Extracellular region |
IEA |
| GO:0042581 |
Cellular Component |
Specific granule |
IEA |
| GO:0050829 |
Biological Process |
Defense response to Gram-negative bacterium |
IEA |
| GO:0050830 |
Biological Process |
Defense response to Gram-positive bacterium |
IEA |
| GO:0051873 |
Biological Process |
Killing by host of symbiont cells |
IEA |
| GO:0044130 |
Biological Process |
Negative regulation of growth of symbiont in host |
IEA |
| GO:0044140 |
Biological Process |
Negative regulation of growth of symbiont on or near host surface |
IEA |
|
Sequence: |
RLKELITTGGQKIGEKIRRIGQRIKDFFKNLQPREEKS |
