CAMPSQ848
Title : Defensin
GenInfo Identifier : 61252268
Source : Phlebotomus duboscqi [Sandfly]
Taxonomy : Animalia, Insects
NCBI Taxonomy : 37738
UniProt: P83404
PubMed : 15557638
Length : 40
Activity : Antibacterial, Antifungal
Gram Nature : Gram+ve
Target : S. aureus ( MIC = 0.78-1.56 microM) , Aspergillus fumigatus ( MIC = 12.5-25 microM) , F. culmorum ( MIC = 1.56-3.12 microM) , F. oxysporum ( MIC = 3.12-6.25 microM), Neurospora crassa ( MIC = 6.25-12.5 microM) , T. viride ( MIC = 3.12-6.25 microM) , Trichophyton mentagrophytes ( MIC = 25-50 microM), Candida albicans ( MIC = 6.25-12.5 microM) , S. cerevisiae ( MIC = 25-50 microM) , L. major promastigote forms ( IC50 = 68-85 microM)
Validated : Experimentally Validated
Pfam : PF01097 : ( Arthropod defensin )
InterPro : IPR001542 : Defensin_invertebrate/fungal.
IPR003614 : Scorpion_toxin-like.
AMP Family : Defensin
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular Component Extracellular region IDA
GO:0050832 Biological Process Defense response to fungus IDA
GO:0050830 Biological Process Defense response to Gram-positive bacterium IDA
GO:0045087 Biological Process Innate immune response IEA
GO:0031640 Biological Process Killing of cells of other organism IEA
Sequence:
ATCDLLSAFGVGHAACAAHCIGHGYRGGYCNSKAVCTCRR