Tachystatin-A2

CAMPSQ880

Title :

Tachystatin-A2

GenInfo Identifier :

74849791

Source :

Tachypleus tridentatus [Japanese horseshoe crab]

Taxonomy :

Animalia

NCBI Taxonomy :

6853

UniProt:

Q9U8X3

PDB:

1CIX

Structure Database :

CAMPST5

PubMed :

10473569 , 11959852

Length :

Activity :

Antibacterial, Antifungal

Gram Nature :

Gram+ve, Gram-ve

Target :

S.aureus ( IC50 = 4.2 microg/ml) , C.albicans ( IC50 = 3.0 microg/ml) , P.pastoris ( IC50 = 0.5 microg/ml), E.coli ( IC50 = 25 microg/ml)

Hemolytic Activity :

No hemolysis of sheep erythrocytes

Validated :

Experimentally Validated

Pfam :

PF11406 : ( Antimicrobial peptide tachystatin A )

InterPro :

IPR022717 : Antimicrobial_tachystatin_A.
IPR009030 : Growth_fac_rcpt_N_dom.

AMP Family :

Tachystatin

Signature :

ID	Type	Pattern / HMM	T. Length
CAMPTacH	HMM		Variable

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005576	Cellular Component	Extracellular region	IEA
GO:0042742	Biological Process	Defense response to bacterium	IEA
GO:0050832	Biological Process	Defense response to fungus	IEA
GO:0031640	Biological Process	Killing of cells of other organism	IEA

Sequence:

YSRCQLQGFNCVVRSYGLPTIPCCRGLTCRSYFPGSTYGRCQRY