| CAMPSQ983 |
| Title : |
Hepcidin-25 / LEAP |
| GenInfo Identifier : |
159162673 |
| Source : |
Homo sapiens [Human] |
| Taxonomy : |
Animalia, Mammals |
| UniProt: |
P81172 |
| PDB: |
1M4E, 1M4F, 2KEF, 3H0T |
| Structure Database : |
CAMPST37, CAMPST38, CAMPST170, CAMPST263 |
| PubMed : |
11034317 , 11113131 |
| Length : |
25 |
| Activity : |
Antibacterial, Antifungal |
| Gram Nature : |
Gram+ve, Gram-ve |
| Target : |
E.?coli ML35p, S. epidermidis, S. aureus, C. albicans, group B Streptococcus , Neisseria cinerea , Saccharomyces cerevisiae ( MIC = 50 mg/ml) , B.subtilis ( MIC = 40 mg/ml ) |
| Validated : |
Experimentally Validated |
| Comment : |
Inactive against Pseudomonas aeruginosa , Rhodotorula rubra , Escherichia coli BL21 , Pseudomonas fluorescens |
| Pfam : |
PF06446 : ( Hepcidin )
|
| InterPro : |
IPR010500 : Hepcidin.
|
| AMP Family : |
Hepcidin |
| Signature : |
| ID |
Type |
Pattern / HMM |
T. Length |
|
CAMPHepH |
HMM |
 |
Variable |
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005576 |
Cellular Component |
Extracellular region |
NAS |
| GO:0006879 |
Biological Process |
Cellular iron ion homeostasis |
IEA |
| GO:0042742 |
Biological Process |
Defense response to bacterium |
IEA |
| GO:0050832 |
Biological Process |
Defense response to fungus |
IEA |
| GO:0006955 |
Biological Process |
Immune response |
TAS |
| GO:0031640 |
Biological Process |
Killing of cells of other organism |
IEA |
|
Sequence: |
DTHFPICIFCCGCCHRSKCGMCCKT |
